Roland Fasol
While my primary expertise lies in complex cardiovascular surgeries, I also possess extensive experience in building and managing medical teams and spearheading the development of hospital infrastructure, including planning, equipment procurement, information technology, and the implementation of new marketing and patient information solutions. Additionally, I have worked extensively on setting clinical governance standards and establishing cost and quality control mechanisms.
I earned my medical degree from the Medical University of Vienna and a post-PhD teaching license (Habilitation) from the University of Freiburg, Germany, where I also became a fully qualified cardiac surgeon. My training was conducted at institutions such as the Universities of Vienna, Hong Kong, Cape Town, and Freiburg.
Early in my career, I served as a war surgeon at a Red Cross field hospital during the Cambodian jungle guerrilla war on the Thailand-Cambodian border.
Served as deputy head at Europe's largest heart center (Rhön-Clinic) in Bad Neustadt, recognized as one of Europe's best managed and financially most successful centers at that time in order to learn modern medical management methods and medical cost management, parallel to refining his practise as heart surgeon in a high volume center.
My leadership roles include launching and leading the Heart Center in Ingolstadt, Germany; being an entrepreneur and CEO in the development of a private Austrian Heart Center in collaboration with the US Cleveland Clinic and InterContinental Hotel Group; and establishing hospitals in Tirana, Albania; Changchun, China; the Maldives; and Papua New Guinea.
I also served as Director of Health on St Helena, analyzing and recommending cost-effective restructuring for the island's healthcare system.
As Vice President of Medical Affairs at Medpoint Asia, I also acted as Chief Medical Officer for the R&F Hospital in Guangzhou, China, in association with UCLA Health, where I facilitated the opening of this international hospital.
Since summer 2023, I have been appointed by the Medical University Vienna International as Chief Medical Officer for the startup of the private ASA Hospital in Sarajevo, Bosnia. In the six months since opening, the hospital has seen a monthly increase in patient numbers and revenue of approximately 30-40%.
Alongside my clinical work, I maintained an active program of medical research. I have set up basic research laboratories in Vienna, Cape Town, and Freiburg, pioneering tissue engineering and gene technology clinical studies. I have served as a medical advisor to various US medical companies and startups and have received 24 international awards and research grants. My academic contributions include nearly 300 publications, with roughly 100 as original articles and abstracts.
- - -
- legally entitled to practice medicine as specialist in surgery in Austria (Austrian Medical Chamber)
- Licensed General and Cardiac Surgeon (Austrian Doctors Association & Chamber of Physicians - Bavaria, Germany)
- “Approbation“ - Permanent License to Practice as Physician (Ministry of Health Bavaria, Germany)
- UK GMC Specialist Registry No 6095355 (General & Cardiothoracic Surgery)
- Chinese temporary Physician License No 2012006
- Maldives Medical & Dental Council Practicing License No PL01743 - TMR 3814 (Basic Medical, General & Cardiac Surgery)
- “Habilitation“ - Venia Legendi (University Lecturer) - for Thoracic and Vascular Surgery, University of Freiburg, Germany
- since 2023 - 'Professor' Medical University of Vienna
email: roland@fasol.us
Experience
. . . appointed by the Medical University Vienna International as Chief Medical Officer (CMO) to start up the private ASA Sarajevo Hospital in Sarajevo, Bosnia.
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Vice President Medical Affairs - Medpoint Asia. As part of this role Chief Medical Officer (CMO) for the R&F Hospital in Guangzhou to start up this specialist, private international hospital. Combined with this up to 500 bed international hospital there are 3 buildings with about 500 condominiums for retired senior citizen, including a rehabilitation center and 24hr care.
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Was appointed for an interim 6 month period to restructure & reorganize the St Helena health care system, organization and structure. Following the strategic analysis of the health directorate to become more cost effective, started to work for a change to an independently managed not-for-profit but commercially minded operation with the need to introduce a health insurance arrangement. Furthermore, initiated to start the process to shift from a pure therapeutic concept to a preventive outlook of medicine on the St Helena island. other Activities: Started weekly newspaper columns for the local newspaper to inform about COVID preparedness and home quarantine
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Joined to re-organize this tertiary private Hospital. All medical staff and auxiliary services report to me. Main purpose is to reorganize patient services to improve quality and outcome, prepare and organize the hospital for accreditation by starting a substantial clinical governance and quality control program and organize a cardiac team to start the only cardiac surgery service in the country. Organize the PR work of the hospital, start new marketing initiatives and start training programs for young local doctors.
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Pre-opening and opening as well as logistics and medical start-up of the Hospital and Surgical Department – preparing the JCI accreditation of the hospital. I was hired 8 month before planned opening to organize the cardiac department. Within 1 month my responsibilities were expanded to overall responsibility for the whole hospital as Medical Director / CMO.
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One of the first non-Chinese doctors to head a new private heart hospital in China. The Jilin Heart Hospital was one of the first private special hospitals in China at that time. Organized the logistics and medical start-up of a 300 bed, 40 ICU bed, specialized cardiac center for adult and pediatric cardiology and cardiac surgery. The Jilin Heart Hospital became University Teaching Hospital of the Jilin Beihua University in 2015.
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Organized the pre-opening of this hospital and started this specialized cardiac hospital from an empty building to the first successful surgery in 6 month and turned it into the leading cardiac center in Albania at that time.
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Invited as visiting cardiac consultant to the cardiac surgery department at the Kind Faisal Hospital and Research Center in Jeddah and was flown to Riyadh and asked to apply for the position as head of department.
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Part-time consultant cardiac surgeon responsible for all adult cardiac operations - specifically complex mitral valve repair procedures, and assisting, training of young doctors.
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Part-time visiting consultant cardiac curgeon in Skopje at this new cardiac surgery program - operating up to 4-5 open heart operations per day myself and helping to train young doctors.
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Parallel to working as a cardiac surgeon in Vienna and Skopje I had my main interest as CEO and entrepreneur for the start-up project development of a private Heart Centre & combined hotel in Austria. This venture, in cooperation with the US Cleveland Clinic Foundation (CCF) and the InterContinental Hotel Group (IHG) was aiming to realize a highly specialized private Cardiac Centre in Austria. A 150 bed private medical facility in combination with a 200 bed hotel was developed up to the finalized bank financing [62 Mio€ bank leasing and raised seed investment of 22 Mio€] with all permissions for realization and starting construction. The project was sold to an Austrian government group - the new hospital opened as psychosomatic clinic in 2011.
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Part-time visiting consultant cardiac curgeon at the city hospital Vienna-Lainz parallel my main interest as CEO and entrepreneur to start a a private Heart Centre.
Read MoreAwards
2023 appointed Professor - by the Medical University of Vienna, Austria
2015 'Lifetime Emeritus status' - awarded by the board of the International Society for Applied Cardiovascular Biology (isacb.org) for outstanding contributions
2014 'Changbai Friendship Award' - awarded by the Dept of human resources, the foreign affairs office Government of Jilin Province, China
2013 'Outstanding Medical Contribution Award’ - awarded by the health bureau of Changchun, Jilin Province, China
2013 'Changchun Friendship Award' - awarded by the bureau of foreign expert affairs, Jilin Province, for contributions to developments of Changchun, China
1996 'Goedecke Park Davis Grant' - for the program: “Postoperative application of calcium-antagonists Diltiazem in coronary patients: evaluation of anti-arrhythmic effects“
1995 'German-Israeli Research Foundation' - awarded for the cooperation program: “Vascular Gene Therapy“
1995 'Ludwig Heilmeyer Award' - by the University of Freiburg for the MD-Thesis supervised by me: “The functional importance of the Renin-Angiotensin system in the human myocardium. Experiments on the isolated atrial and ventricular tissue under physiological conditions“
1994 'Goedecke Park Davis Grant' - for the program: “Perioperative application of Diltiazem in aortocoronary bypass patients: evaluation of the anti-arrhythmic and anti-ischemic properties“
1993 'Finlandia Award' - by the 'Association of International Vascular Surgeons' for the conference-paper: “Advanced genetic engineering technology may help to develop new concepts in cardiovascular surgery“
1993 'Förderpreis ‘Studenten Forschen’' - by the State Council for Research and Art of the County of Sachsen, Germany, for the MD-Thesis supervised by me. “Experimental use of the angiogenic growth factors for in vivo culture of functional blood vessels“
1992 'Hancock Award' - by the 'German, Austrian & Swiss Society of Thoracic and Cardiovascular Surgeons' for the conference paper: “Experimental study of the angiogenetic growth factor HBGF-I for the in-situ and in-vivo cultivation of new functional blood vessels“
1992 'Poster Award' - by the 'Society of Bavarian Surgeons' for the poster: “In vivo culture of new coronary blood vessels by applying angiogenetic growth factors“
1992 'Dos Santos´s Award' - by the 'European Society for Cardiovascular Surgery' for the conference-paper: “Can you grow new arteries for cardiovascular surgeons? Experimental study of arterial 'in situ' growth by the angiogenic growth factor HBGF-I“
1992 'GENSIA Grant' - for the program: “A study of the effects of Acadesine on myocardial ischemia and clinical outcomes in patients undergoing coronary artery bypass“
1992 'International Guest Scholar' - by the 'American College of Surgeons' for outstanding surgical research.
1991 'Goedecke Park Davis Grant' - for the program: “Perioperative application of calcium-antagonists in coronary artery bypass patients“
1990 'Alexis Carrel Award' - by the 'German Society of Thoracic & Cardiovascular Surgeons' for the paper: “The confluent lining of vascular grafts with endothelial cells: A preclinical study“
1990 'Anton v. Eiselsberg Award' - by the 'Austrian Van Swieten Society' & the ‘Austrian Doctors Association' for the paper: “Growth properties of cultured human endothelial cells on differently coated artificial heart materials“
1989 'Sigma-Tau Young Investigator Award' - by the 'International Union of Angiology' for the paper: "Reduced reproductive capacity of freshly harvested endothelial cells in smokers”
1988 'Theodor v. Billroth Award' - by the 'Austrian Society of Surgeons' for the paper: "In vitro endothelialization of PTFE vascular grafts"
1988 'Wissenschaftlicher Fonds' - grant by the Major of the City of Vienna "The physiological and non-thrombogenic vascular prosthesis"
1988 'Fondprojekt' - grant by the National Research Fund Austria: "Endothelialization of biological heart valves"
1988 'Jubiläumsfond Project Award' - grant by the Austrian National Bank: "Application of angiogenetic growth factors in surgical research"
1984 'Jubiläumsfond Project Award' - grant by the Austrian National Bank: "Surgically relevant endothelial cell cultivation"
Links
Ludwig BOLTZMANN
Ludwig Boltzmann (1844–1906) is generally acknowledged as one of the most important physicists of the nineteenth century. In his youth Ludwig Boltzmann took piano lessons from Anton Bruckner.
nominated for the Nobel Prize: 1903, 1905, 1906
Ottokar Freiherr von CHIARI
Ottokar Freiherr von Chiari (1853-1918) professor at the University of Vienna and founder of the Laryngological (ENT) clinic, pioneer of transbronchial surgery and personal physician of the emperor Franz-Josef I of Austria. He was a younger brother to pathologist Hans Chiari (1851–1916) and the son of gynecologist Johann Baptist Freiherr von Chiari (1817–1854) - Professor at the University of Prague and teacher of Ignatz Semmelweis who discovered puerperal fever [childbed fever].
Karl Freiherr von CHIARI
Karl Freiherr von Chiari (1912-1982) professor at the University of Vienna, pioneer of pelvic osteotomy surgery and founder of the Orthopaedic clinic at the University of Vienna and regarded as the founder of modern orthopaedics. He was the grandchild of Ottokar Freiherr von Chiari (1853-1918).
Hans Freiherr von CHIARI
Hans Freiherr von Chiari (1851-1916) was an Austrian pathologist. He made important contributions in endocrinology, cardiology and neurology. Eponymously affiliated with the Chiari malformations; Type II Chiari malformation (Arnold-Chiari syndrome) and Budd-Chiari syndrome.
Kids
Pia Florencia FASOL
Artist ▫︎ graduated with honors from De La Salle University - College of Saint Benilde, Manila, Philippines ◦ Masters in Luxury & Fashion Brand Management - Instituto Marangoni, Milano, Italy
school in Germany & graduated in Krems, Austria ◦ studied & graduated Bachelor of Arts & Major in Fashion Design & Merchandising - De La Salle University Manila ◦ Freelance Fashion & Graphic Designer ◦ Production Manager for DLS-CSB College Graduation Fashion Show Manila ◦ SM Shoe Mart Department Stores Photography, Marketing Department, Manila ◦ AWARDS - 2006 “Move On” Leadership by the Austrian Student Union ◦ 2013 Finalist for Evening Wear Design Category, Miss NCAA, Theme- and Evening Wear Competition, Manila, Philippines
Lisa P. FASOL
Illustrator/Animator ▫︎ graduated with honors from Rhode Island School of Design, Providence, RI, US
school in Krems, Austria & Tirana International School Albania & graduated from Manila International School, Philippines ◦ 3D Graphic Design, Animation & Special Effects - Stanford University, US ◦ studied Mandarin at Northwest University Changchun, China ◦ studied at RISD & graduated ‘Bachelor of Fine Arts & Illustration’ ◦ employed by dotdash.com - Boston, US ◦ published in The New York Times ◦ AWARDS & RECOGNITIONS ◦ 2016 SOKI International Design & Illustration Competition ◦ 2019 American Illustration 38 ◦ 2019 NYC Society of Illustrators Student Competition [www.lisa-fasol.com]
Noell Juanito FASOL
Student
school in Krems, Austria & Tirana International School Albania ◦ 3D Graphic Design, Animation & Special Effects - Stanford University, US ◦ Delegate Harvard National Model UN Conference Beijing, China ◦ graduated American Int School Changchun, China ◦ experimental medical research Nanyang Technological University Singapore (published and co-authored 4 peer-reviewed publications) ◦ studied medicine at the Sigmund Freud University Vienna, Austria ◦ switched to study ‘Visual Effects and 3D Animation’
PUBLICATIONS
Publications (Full length, peer-reviewed publications)
1. "Comparison of the effects of Dihydroergotamine and Ergonovine on functional changes caused by ß-adrenergic stimulation in normally and underperfused canine myocardium" ✧ J Cardiovasc Pharmacol 6:384-391 (1984) ✧ Seitelberger R, Schlappak O, Fasol R, Raberger G
2. "Experimental in vitro cultivation of human endothelial cells on artificial surfaces" ✧ Trans Am Soc Artif Intern Organs 31:257-284 (1985) ✧ Fasol R, Zilla P, Groscurth P, Wolner E, Moser R
3. "Ectopic parvalbumin positive cells in the cerebellum of the adult mutant mouse ´nervous´" ✧ Acta Anatomica 124:181-187 (1985) ✧ Zilla P, Celio MR, Fasol R, Zenker W
4. "Enzyme activities of purine catabolism and salvage in human muscle tissue" ✧ Adv Exp Med Biol 195B:507-509 (1986) ✧ Schopf G, Havel M, Fasol R, Müller MM
5. "Laser-induced lesions by VW-ND Yag or pulsed UV lasers during angioplastic procedures" ✧ Thorac Cardiovasc Surg 34:63-65 (1986) ✧ Wollenek G, Laufer G, Fasol R, Zilla P, Wolner E
6. "Der klinische Einsatz der Endothelzell-Kultivierung beim Alloplastischen Gefäßersatz" ✧ Angio 8:337-341 (1986) ✧ Zilla P, Fasol R, Minar E, Kadletz M, Fischlein T
7. "Protein C system in patients undergoing cardiopulmonary bypass surgery" ✧ J Thorac Cardiovasc Surg 94:600-605 (1987) ✧ Knöbl P, Zilla P, Fasol R, Müller MM, Vukovich Th
8. "Klinischer Einsatz des intraoperativen Endothelzell-Seedens von e-PTFE Gefäßprothesen" ✧ Angio 2:113-117 (1987) ✧ Fasol R, Zilla P, Fischlein T, Preiss P, Kadletz M, Krupicka O, Schreiner W, Kähler J
9. "Endothelial cell seeding of PTFE vascular grafts in humans: a preliminary report" ✧ J Vasc Surg 6:535-541 (1987) ✧ Zilla P, Fasol R, Deutsch M, Fischlein T, Minar E, Hammerle A, Krupicka O, Kadletz M
10. "Twenty years of heart transplantation at the Groote Schuur Hospital" ✧ J Heart Transplant 6:317-323 (1987) ✧ Reichenspurner H, Odell J, Cooper D, Novitzky D, Human P, Becerra E, Böhm D, Rose A, Fasol R, Zilla P, Reichart B
11. "Scanning electron microscopy of circulating platelets reveals new aspects of platelet alteration during cardio-pulmonary bypass operations" ✧ J Tex Heart Inst 14:13-2 (1987) ✧ Zilla P, Fasol R, Hammerle A, Yildiz S, Kadletz M, Laufer G, Wollenek G, Seitelberger R, Deutsch M
12. "Endothelialization of artificial surfaces: does surface tension determine growth of HSVEC?" ✧ J Tex Heart Inst 14:119-126 (1987) ✧ Fasol R, Zilla P, Deutsch M, Fischlein T, Kadletz M, Griesmacher A, Müller MM
13. "Characterization of an interferon resistant mutant of the human cancer cell line bt-20" ✧ J Interferon Res 7:195-202 (1987) ✧ Marth C, Gastl G, Zech J, Zilla P, Fasol R, Huber C, Daxenbichler G
14. "PGi2 and PGe1 induce morphological alterations in human platelets similar to those observed in the initial phase of activation" ✧ Exp Haematol 15:741-749 (1987) ✧ Zilla P, Groscurth P, Varga G, Fischlein T, Fasol R
15. "In vitro lining of Fibronectin coated PTFE grafts with cryopreserved endothelial cells" ✧ Thorac Cardiovasc Surg 35:143-147 (1987) ✧ Kadletz M, Moser R, Preiss P, Deutsch M, Zilla P, Fasol R
16. "Plaque ablation by eximer laser irradiation using a movable energy-transmitting device" ✧ J Tex Heart Inst 14:47-52 (1987) ✧ Laufer G, Wollenek G, Stangl G, Klepetko W, Fasol R, Zilla P, Wolner E
17. "In vitro Endothelialisierung von PTFE Kunststoffprothesen" ✧ Angio 4:159-168 (1988) ✧ Fasol R, Zilla P, Fischlein T
18. "The anomalous left superior vena cava in combined heart-lung transplantation" ✧ J Heart Transplant 7:445-447 (1988) ✧ von Oppell U, Odell JA, Reichenspurner H, Reichart B, Zilla P, Fasol R
19. "Thoraco-abdominal injuries in combat casualties on the Cambodian border" ✧ Thorac Cardiovasc Surg 36:33-36 (1988) ✧ Fasol R, Zilla P, Irvine S, von Oppell U
20. "Whole blood aggregometry and platelet adenine nucleotides during cardiac operations" ✧ Scand J Thoracic Cardiovasc Surg 22:165-170 (1988) ✧ Zilla P, Fasol R, von Oppell U, Knöbl P, Vukovich T, Laufer G, Wollenek G, Hammerle A, Müller MM
21. "Impacts of low-dose steroids and prophylactic monoclonal versus polyclonal antibodies on acute rejection in cyclosporine and azathioprine-immunosuppressed cardiac allografts" ✧ J Heart Transplant 8:253-261 (1989) ✧ Laufer G, Laczkovics A, Wollenek G, Schreiner W, Sochor H, Buchelt M, Fasol R, Wolner E
22. "Blood platelets in cardiopulmonary bypass operation: recovery occurs after initial stimulation rather than continual activation” ✧ J Thorac Cardiovasc Surg 97:379-388 (1989) ✧ Zilla P, Fasol R, Groscurth P, Klepetko W, Reichenspurner H, Wolner E
23. "Reduced reproductive capacity of freshly harvested endothelial cells in smokers - a possible shortcomming in the success of seeding?” ✧ J Vasc Surg 10:143-148 (1989) ✧ Zilla P, Siedler S, Fasol R, Sharefkin JB
24. "Das infrarenale Aortenaneurysma: Chirurgische Behandlungsergebnisse" ✧ Wiener Klinische Wochenschrift 101:66-69 (1989) ✧ Deutsch M, Holzinger Ch, Krisch B, Magometschnigg H, Fasol R, Zilla P, Schwartz Ch, Staudacher M
25. "Human endothelial cell seeding: evaluation of it's effectiveness by platelet parameters after one year” ✧ J Vasc Surg 9:432-436 (1989) ✧ Fasol R, Zilla P, Deutsch M, Grimm M, Fischlein T, Laufer G
26. "Surface morphology of circulating platelets: a suggested parameter for the monitoring of endothelial cell seeded grafts” ✧ J Cardiovasc Surg 30:398-401 (1989) ✧ Fasol R, Zilla P, Fischlein T, Laufer G, Deutsch M
27. "Vascular injuries caused by anti-personnel mines" ✧ J Cardiovasc Surg 30:467-472 (1989) ✧ Fasol R, Irvine S, Zilla P
28. "Anti-personnel mine injuries" ✧ Asian J Surg 12(1):1-7 (1989) ✧ Fasol R, Zilla P
29. "Use of fibrin glue as a substrate for in vitro endothelialization of PTFE vascular grafts" ✧ Surgery 105:515-522 (1989) ✧ Zilla P, Fasol R, Preiss P, Kadletz M, Deutsch M, Schima H, Tsangaris S, Groscurth P
30. "Precoating substrate and surface configuration determine adherence and spreading of seeded endothelial cells on PTFE grafts" ✧ J Vasc Surg 9:535-541 (1989) ✧ Kähler J, Zilla P, Fasol R, Deutsch M, Kadletz M
31. "Characteristics of 308 nm-excimerlaser activated arterial tissue photoemission under ablative and non-ablative conditions" ✧ J Vasc Surg 9:535-541 (1989) ✧ Laufer G, Wollenek G, Rückle B, Hohla Ch, Buchelt M, Ruatti H, Fasol R, Wolner E
32. "In-situ canulation, microgrig follow-up and low density plating provide first passage endothelial cell masscultures for in-vitro lining” ✧ J Vasc Surg 12:180-189 (1990) ✧ Zilla P, Fasol R, Siedler S, Preiss P, Fischlein T, Müller W, Baitella G, Reichart B
33. "Traumatic herniation of the heart into the right pleura - a case report" ✧ Thorac Cardiovasc Surg 38:379-380 (1990) ✧ Fasol R, Lowka K, Nöldge G, Schlosser V
34. "Alogenic, multidonor in vitro endothelialization of small diameter PTFE grafts in baboons" ✧ Vasc Surg 25:64-71 (1991) ✧ Fasol R, Zilla P, Preiss P, Odell J, Reichart B
35. "Growth properties of cultured human endothelial cells on differently coated artificial heart materials" ✧ J Thorac Cardiovasc Surg 101:671-680 (1991) ✧ Zilla P, Fasol R, Grimm M, Fischlein T, Eberl T, Preiss P, Krupicka O, v. Oppell U, Deutsch M
36. "Experimental in vitro endothelialization of cardiac valve leaflets" ✧ Ann Thorac Surg 53:487-492 (1992) ✧ Eberl T, Siedler S, Schumacher B, Zilla P, Schlaudraff K, Fasol R
37. "The influence of obesity on perioperative morbidity: retrospective study of 502 aorto-coronary bypass operations” ✧ Thorac Cardiovasc Surg 40:126-129 (1992) ✧ Fasol R, Schindler M, Schumacher B, Hannes W, Seitelberger R, Schlosser V
38. "Diltiazem provides antiischemic and antiarrhythmic protection in patients undergoing coronary bypass grafting” ✧ Eur J Cardio-thorac Surg 7:239-245 (1993) ✧ Hannes W, Fasol R, Zajonc H, Schlosser V, Holubarsch Ch, Seitelberger R
39. "Aortic aneurysm repair in patients with coronary heart disease: strategy for treatment" ✧ Vasc Surg 27:344-349 (1993) ✧ Schlosser V, Fraedrich G, Schindler M, Fasol R
40. "Angiotensin II has positive effects in atrial but not in ventricular human myocardium" ✧ Circulation 88:1228-1237 (1993) ✧ Holubarsch Ch, Hasenfuss G, Pieske B, Schmidt-Schweda S, Fasol R, Just H
41. "Growth of 'new' coronary vascular structures by angiogenetic growth factors" ✧ Eur J Cardio-thorac Surg 7:637-643 (1993) ✧ Schlaudraff K, Schumacher B, v. Specht BU, Seitelberger R, Schlosser V, Fasol R
-> Editorial Comment Eur J Cardio-thorac Sur 7:644 (1993)
42. "Auftreten transienter organischer Psychosyndrome nach koronarer Bypass-Operation" ✧ Intensivmed 30:318-322 (1993) ✧ Walzer T, Herrmann M, Fasol R, Hannes W, Wallesch CW
43. "Perioperative myocardial protection with continuous infusion of Diltiazem in coronary bypass surgery” ✧ A Cardiovasc Thorac Ann 4:174-179 (1993) ✧ Seitelberger R, Hannes W, Fasol R
44. "Effects of Diltiazem on perioperative ischemia, arrhythmias and myocardial function in patients undergoing elective coronary bypass grafting” ✧ J Thorac Cardiovasc Surg 107:811-821 (1994) ✧ Seitelberger R, Hannes W, Gleichauf M, Keilich M, Christoph M, Fasol R
45. "Shed blood autotransfusion influences ischemia-sensitive laboratory parameters after coronary operations” ✧ Ann Thorac Surg 57:1289-1294 (1994) ✧ Hannes W, Keilich M, Köster W, Seitelberger R, Fasol R
46. "Necrotising pancreatitis due to ruptured abdominal aortic aneurysm" ✧ Eur J Vasc Surg 8:521-523 (1994) ✧ Gruber H, Fasol R, Schlosser V
47. "Effects of Diltiazem on perioperative ischemia, arrhythmias and myocardial function in patients undergoing elective coronary bypass grafting” ✧ Drugs Today 30(Suppl A):11-23 (1994) ✧ Seitelberger R, Hannes W, Gleichauf M, Fasol R
48. "Experimental use of a modified fibrin glue to induce site-directed angiogenesis from the aorta to the heart" ✧ J Thorac Cardiovasc Surg 107:1432-1439 (1994) ✧ Fasol R, Schumacher B, Hauenstein KH, Seitelberger R
49. "In vitro-lined endothelium: initial integrity and ultrastructural events" ✧ Surgery 116:524-534 (1994) ✧ Zilla P, Preiss P, Groscurth P, Rosemeier F, Deutsch M, Odell J, Heidinger C, Fasol R, v. Oppell U
50. "Functional significance of angiotensin receptors in human myocardium: significant differences between atrial and ventricular myocardium” ✧ Eur Heart J 15:88-9 (1994) ✧ Holubarsch Ch, Schmidt-Schweda S, Knorr A, Fasol R, Hasenfuss G, Just H
51. "Stellenwert der perioperativen Applikation des Kalziumantagonisten Diltiazem bei aorto-koronaren Bypassoperationen” ✧ Herz- Thorax-Gefäßchir 8:185-199 (1994) ✧ Fasol R, Seitelberger R
52. "Effect of perioperative Diltiazem on myocardial ischemia and function in patients receiving mammary artery grafts” ✧ Eur Heart J 16:87-93 (1995) ✧ Hannes W, Seitelberger R, Christoph M, Keilich M, Kulinna Ch, Holubarsch Ch, Fasol R
53. "Acadesine: a new drug that may improve myocardial protection in coronary artery bypass grafting. Results of the first international multicenter study” ✧ J Thorac Cardiovasc Surg 110:1096-1106 (1995) ✧ Menasché P et al, on behalf of the multinat. study group (Fasol R et al)
54. "In vitro edothelialization of bioprosthetic heart valves" ✧ J Heart Valve Dis 5:58-65 (1996) ✧ Fischlein T, Fasol R
55. "Postoperative follow-up of coronary patients receiving calcium antagonist Diltiazem" ✧ IJA 6:8-12 (1997) ✧ Keilich M, Kulinna Ch, Seitelberger R, Fasol R
56. "Papillary muscle shortening plasty for mitral valve reconstruction in patients with ischaemic mitral insufficiency” ✧ Europ Heart J 19:1730-1734 (1998) ✧ Fasol R, Wild T, Pfannmüller B, Stumpf J, Hacker R
-> Editorial Comment Europ Heart J 19:1598-1599 (1998)
57. "Anti-ischaemic and anti-arrhythmic as well as cost-effectiveness of peri-operative Diltiazem in coronary artery bypass patients” ✧ Drugs Today 34[Suppl.E]:19-24 (1998) ✧ Fasol R, Zacher M, Bischoff G, Grunewald M
58. "Early failure of bioprosthesis by preserved mitral leaflets" ✧ Ann Thorac Surg 70:653-654 (2000) ✧ Fasol R, Lakew F
59. "Mitral repair in patients with a ruptured papillary muscle" ✧ Am Heart J 139:549-554 (2000) ✧ Fasol R, Lakew F, Wetter S
60. "Triangular resection of the anterior leaflet for repair of the mitral valve" ✧ Ann Thorac Surg 71:381-383 (2000) ✧ Fasol R, Joubert-Hübner E
61. "Papillary muscle repair surgery in ischemic mitral valve patients" ✧ Ann Thorac Surg 70:771-777 (2000) ✧ Fasol R, Lakew F, Pfannmüller B, Slepian M, Joubert-Hubner E
62. "Trends und Entwicklungen der Mitralklappenchirurge ✧ J Kardiol 7:106-112 (2000) ✧ Fasol R
-> Editorial Comment J Kardiol 7:105 (2000)
63. "Repair of mitral valve billowing and prolapse (Barlow): the surgical technique" ✧ Ann Thorac Surg 74:602-605 (2002) ✧ Fasol R, Mahdjoobian K
64. "Mitral repair in patients with severely calcified annulus: feasibility, surgery and results" ✧ J Heart Valve Dis 10:153-159 (2002) ✧ Fasol R, Mahdjoobian K, Joubert-Hubner E
65. "Left ventricular rupture after mitral surgery: repair by patch and sealing" ✧ Ann Thorac Surg 77:1070-1072 (2004) ✧ Fasol R, Wild T, El Dsoki S
66. "Mitral valve repair with the Colvin-Galloway FutureTM Band" ✧ Ann Thorac Surg 77:1985-1988 (2004) ✧ Fasol R, Meinhart J, Deutsch M, Binder T
67. "A modified and simplified radiofrequency ablation in mitral patients" ✧ J Thorac Cardiovasc Surg 129:215-217 (2005) ✧ Fasol R, Meinhart J, Binder T
-> Editorial Comment J Thorac Cardiovasc Surg 129:1-4 (2005)
68. "Impact of bispectral index monitoring on postoperative delirium in patients undergoing aortic surgery.” ✧ HSR Proc Intensive Care and Cardiovascular Anesthesia 3(1):47-58 (2011) ✧ Santarpino G, Fasol R, Sirch J, Ackermann B, Pfeiffer S, Fischlein T
69. "A cavernous sinus of Valsalva aneurysm" ✧ J Cardiol & Cardiovasc Ther 2(3):555587 (2016) ✧ Fasol R, Bode B, Li X, Fasol N, Seppälä-Lindroos A
70. "Management of massive thrombus formation in a giant left atrium" ✧ J Cardiol Surg 9999:1-2 (2017) ✧ Fasol N, Bode B, Li X, Seppälä-Lindroos A, Fasol R
71. "Follow-up of a Barlow mitral billowing and prolapse repair patient" ✧ Am J Thorac Cardiovasc Surg 2(3):41-44 (2017) ✧ Fasol R, Fasol N, Binder T
72. "Left atrial thrombendarterectomy in rheumatic mitral valve patients" ✧ Open Access J Surg 10(1): OAJS.MS.ID.555783 (2019) ✧ Fasol N, Bode B, Li X, Seppälä-Lindroos A, Fasol R
Other Publications
1. "Letter to the editor - the ISACB annual meeting" ✧ J Vasc Surg 12:705 (1989) ✧ Fasol R
2. "Zur Bedeutung des Endothels auf künstlichen Implantaten in der Herz- & Gefäßchirurgie"✧ Habilitationsschrift, Universität Freiburg (1990) ✧ Fasol R
3. "Anti-Ischämische und anti-Arrhythmische Wirksamkeit des Kalzium-Antagonisten Diltiazem bei aortokoronaren Bypass-operationen" ✧ Dtsch Ärzteblatt 92:A524-527 (1995) ✧ Hannes W, Seitelberger R, Fasol R
4. "Ischämische Mitralklappeninsuffizienz: Verkürzungsplastik der Papillarmuskel" ✧ Symp. Medical Kardiologie 3:28-30 (1999) ✧ Fasol R
5. "Letter to the Editor - Response to the letter of Aoyagi S, et al, Regarding the manuscript ‘Triangular resection of the anterior leaflet for repair of the mitral valve‘ by Fasol R. et al." ✧ Ann Thorac Surg 73:1021 (2002) ✧ Fasol R
6. "Letter to the Editor - Response to the letter of Tanaka K, et al, Regarding the manuscript ‘Repair of mitral valve billowing and prolapse (Barlow): the surgical technique‘ by Fasol R. et al." ✧ Ann Thorac Surg (2006) ✧ Fasol R
Book Editor
1. "Endothelialization of vascular grafts" ✧ S. Karger, Basel (1987) ISBN 3-8055-4557-6 ✧ Zilla P, Fasol R, Deutsch M (Eds.)
2. "Recent advances in cardiovascular surgery" ✧ R.S. Schultz Verlag, München (1989) ISBN 3-7962-0502-X ✧ Reichart B, Fasol R, Odell J, Oppell v. U., Reichenspurner H, Zilla P (Eds.)
3. "Applied cardiovascular biology 1989" ✧ S. Karger, Basel (1990) ISBN 3-8055-5147-9 ✧ Zilla P, Fasol R, Callow AD (Eds.)
4. "Applied cardiovascular biology 1990-91" ✧ S. Karger, Basel (1992) ISBN 3-8055-5430-3 ✧ Zilla P, Fasol R, Callow AD (Eds.)
Book Chapters
1. "Continuous arteriovenous hemofiltration (CAVH) after cardiac surgery" ✧ In: “International Conference on CAVH“, S. Karger (Basel); pp. 116-124 (1985) ✧ Coraim F, Fasol R, Stellwag F, Wolner E
2. "Endothelial cell seeding: experience and first clinical results"✧ In: “Endothelialization of Vascular Grafts“, Zilla P, Fasol R (Eds.); S. Karger; pp. 233-244 (1987) ✧ Fasol R, Zilla P, Deutsch M, Fischlein T, Minar E, Hammerle A, Wolner E
3. "Simulation of pulsatile wall shear stress in peripheral arteries by means of a mock circulation" ✧ In: “Endothelialization of Vascular Grafts“, Zilla P, Fasol R (Eds.); S. Karger; pp. 189-194 (1987) ✧ Schima H, Tsangaris S, Zilla P, Fasol R, Kadletz M
4. "In vitro lining of ptfe grafts with human saphenous vein endothelial cells: physiological shear stress exposure" ✧ In: “Endothelialization of Vascular Grafts“, Zilla P, Fasol R (Eds.); S. Karger; pp. 195-217 (1987) ✧ Zilla P, Fasol R, Kadletz M, Preiss P, Groscurth P, Schima H, Moser R, Griesmacher A, Mostbeck G, Wolner E
5. "Endothelialization of artificial heart materials" ✧ In: “Assisted Circulation 3“, Unger F (Ed), Springer Verlag, pp. 580-598 (1988) ✧ Fasol R, Zilla P
6. "Endothelialization of cardiovascular prostheses"✧ In: "Recent Advances in Cardiovascular Surgery", Reichart B, Fasol R, Zilla P, Reichenspurner H (Eds.) Verlag R.S. Schultz pp. 215-217 (1988) ✧ Fasol R, Zilla P, Reichart B
7. "Cultivation of human endothelial cells on artificial heart materials" ✧ In: "Recent Advances in Cardiovascular Surgery", Reichart B, Fasol R, Zilla P, Reichenspurner H (Eds.) Verlag R.S. Schultz pp. 378-386 (1988) ✧ Fasol R, Zilla P, Grimm M, Preiss P, Fischlein T, Krupicka O
8. "Twenty years of human heart transplantation" ✧ In: "Recent Advances in Cardiovascular Surgery", Reichart B, Fasol R, Zilla P, Reichenspurner H (Eds.) Verlag R.S. Schultz pp. 19-24 (1988) ✧ Reichart B, Reichenspurner H, Odell J, von Oppell U, Human P, Fasol R, Zilla P
9. "Recent advances in immunosuppression after xenogenic heart transplantation in primates" ✧ In: "Recent Advances in Cardiovascular Surgery", Reichart B, Fasol R, Zilla P, Reichenspurner H (Eds.) Verlag R.S. Schultz pp. 137-146 (1988) ✧ Reichenspurner H, Human P, Böhm D, Cooper DKC, Rose AG, May R, Fasol R, Zilla P, Reichart B
10. "Blood platelets during experimental and clinical heart replacement" ✧ In: "Recent Advances in Cardiovascular Surgery", Reichart B, Fasol R, Zilla P, Reichenspurner H (Eds.) Verlag R.S. Schultz pp. 206-212 (1988) ✧ Müller MR, Wohlfart A, Lee A, Zilla P, Fasol R, Wolner E
11. "Surface covering precoating procedures enhance adherence and spreading of seeded endothelial cells on PTFE vascular prostheses"✧ In: "Recent Advances in Cardiovascular Surgery", Reichart B, Fasol R, Zilla P, Reichenspurner H (Eds.) Verlag R.S. Schultz, pp. 341-349 (1988) ✧ Kähler J, Zilla P, Fasol R, Deutsch M
12. "In vitro lining of ptfe grafts with homologous endothelial cells" ✧ In: "Recent Advances in Cardiovascular Surgery", Reichart B, Fasol R, Zilla P, Reichenspurner H (Eds.) Verlag R.S. Schultz, pp. 360-369 (1988) ✧ Zilla P, Fasol R, Preiss P, Dudeck U, Odell J, Sanan D, Reichenspurner H, Reichart B
13. "In vitro endothelialization of vascular prostheses - rapid mass culture technique for autologous endothelial cells and implantation of confluently lined 4-mm PTFE grafts in non-human primates" ✧ In: “Applied Cardiocascular Biology 1989", Zilla P, Fasol R (Eds.) S. Karger; pp. 56-72 (1990) ✧ Zilla P, Fasol R, Preiss P, Reichart B
14. "Jump-grafts und sequentielle Rekonstruktionen der unteren Extremität"✧ In: “Der crurale Gefäßverschluß: aktuelle interdisziplinäre Standortbestimmung” Zehle A (Ed.) W. Zuckschwerdt Verlag, pp. 163-169 (1990) ✧ Deutsch M, Zilla P, Fasol R, Magometschnigg H, Kaliman J, Grabenwöger F, Karnel F
15. "Endothelialisierung von Gefäßprothesen: Biologie kontra Mechanistik" ✧ In: "Gefäßchirurgie im Fortschritt", Maurer PC, Dörrler J (Eds.) Thieme Verlag, pp.123-135 (1990) ✧ Zilla P, Deutsch M, Fasol R
Journal Abstracts
1. "Experimentelle Untersuchungen über den Ursprung des Embolie-Fettes vorwiegend aus Epiphysen langer Röhren-Knochen" ✧ Acta Chir Austr 43:129 (1982) ✧ Fasol R, Gottlob R
2. "Die Grenzflächenspannung zwischen Plasma und Lipiden, Normalwerte und Veränderungen bei verschiedenen Erkrankungen" ✧ Acta Chir Austr 51:93 (1983) ✧ Gottlob R, Appel W, Porschinski K, Fasol R
3. "In vitro cultivation of human endothelial cells on artificial surfaces: first results" ✧ Thorac Cardiovasc Surg 33:97 (1985) ✧ Fasol R, Zilla P, Wollenek G, Laufer G
4. "The laser-induced vascular lesion of cw-nd-yag- and pulsed uv-laser concerning angioplastic procedures" ✧ Thorac Cardiovasc Surg 33:70 (1985) ✧ Laufer G, Wollenek G, Stangl G, Fasol R, Zilla P, Wolner E
5. "Verhalten von Plasmakonzentrationen an Granulozyten-Elastase während Extra-korporaler Zirkulation" ✧ Thorac Cardiovasc Surg 33:65 (1985) ✧ Havel M, Graninger W, Moritz A, Fasol R, Müller MM
6. "Morphologische und Funktionelle Thrombocyten-Veränderungen bei Kardiochirurgischen Operationen mit Extrakorporaler Zirkulation" ✧ Der Anaesthesist 34:212 (1985) ✧ Hammerle A, Fasol R, Zilla P
7. "Effects of interferons on tumor cells in culture" ✧ J Exp Clin Hematol 51:154 (1985) ✧ Marth Ch, Gastl G, Zilla P, Fasol R, Mayer I, Huber Ch
8. "Flow and material dependence of platelet morphology, adenine nucleotides, PF4, ßTG and whole blood aggregometry" ✧ Trans Am Soc Artif Intern Org 32:26 (1986) ✧ Fasol R, Zilla P, Hammerle A, Wollenek G, Laufer G, Deutsch Wolner E
9. "Long term angiographic follow-up after complex crural reconstructions" ✧ Thorac Cardiovasc Surg 35:87 (1987) ✧ Deutsch M, Fasol R, Grabenwöger F, Kaliman J, Kumpan W, Wollenek G, Zilla
10. "Development of a new operation technique for endothelialization of e-PTFE vascular grafts with autologous endothelial cells: shear stress exposure and first clinical results" ✧Thorac Cardiovasc Surg 35:83-84 (1987) ✧ Zilla P, Fasol R, Kadletz M, Deutsch M, Wollenek G, Laufer G, Griesmacher A, Müller MM
11. "Experimental model for the endothelialization of biological heart valve leaflets" ✧ Thorac Cardiovasc Surg 40:137 (1992) ✧ Schumacher B, Schlaudraff K, Hannes W, Seitelberger R, v. Specht BU, Schlosser V, Fasol R
12. "An experimental study of in situ and in vivo growth of “new arteries“ by the angiogeneic growth factor HBGF-I" ✧ Thorac Cardiovasc Surg 40:136 (1992) ✧ Schlaudraff K, Hannes W, Seitelberger R, v. Specht BU, Schlosser V, Fasol R
13. "Antiischaemic and antiarrhythmic properties of the calcium-antagonist diltiazem in aortocoronary bypass patients" ✧Thorac Cardiovasc Surg 40:121 (1992) ✧ Hannes W, Schumacher B, Schlaudraff K, Fasol R, Schlosser V, Seitelberger R
14. "Experimental growth of 'new' coronary arteries by surgically implanted angiogenic growth factors" ✧ Europ Heart J 13(Suppl):158 (1992) ✧ Schlaudraff K, Schumacher B, Hauenstein KH, Seitelberger R, Schlosser V, Fasol R
15. "Antiischemic and antiarrhythmic potency of diltiazem in aortocoronary bypass grafting" ✧ Europ Heart J 13(Suppl):158 (1992) ✧ Seitelberger R, Hannes W, Schindler M, Schumacher B, Fasol R, Schlosser V
16. "Biolization of biological heart valves: an experimental study" ✧ Europ Heart J 13(Suppl):140 (1992) ✧ Schumacher B, Schlaudraff K, Seitelberger R, v.Specht BU, Schlosser V, Fasol R
17. "Can you grow new arteries for cv surgeons? experimental study of arterial in situ growth by the angeogenetic growth factor HBGF-I" ✧ J Cardiovasc Surg 33(Suppl):47 (1992) ✧ Schlaudraff K, Seitelberger R, v.Specht BU, Schlosser V, Fasol R
18. "Experimental in vitro endothelialization of biological heart valves" ✧ J Cardiovasc Surg 33(Suppl):48 (1992) ✧ Schumacher B, Schlaudraff K, Seitelberger R, v.Specht BU, Schlosser V, Fasol R
19. "Retransfusion of mediastinal shed blood has a significant influence on cardiac enzyme levels in postoperative coronary artery bypass patients" ✧ Thorac Cardiovasc Surg 41(Suppl):106 (1993) ✧ Keilich M, Seitelberger R, Hannes W, Fasol R
20. "Influence of surgical vein handling on growth and function of human saphenous vein endothelial cells" ✧ Thorac Cardiovasc Surg 41(Suppl):108-109 (1993) ✧ Schumacher B, Schlaudraff K, Seitelberger R, Schmitt-Pilger H, Schlosser V, Fasol R
21. "Growth factor precoating and in vitro endothelialization prevents degeneration of alternatively preserved biological heart valves" ✧ Thorac Cardiovasc Surg 41(Suppl):146 (1993) ✧ Schlaudraff K, Schumacher B, Schlosser V, Fasol R
22. "Wertigkeit verschiedener diagnostischer Methoden zur Erfassung der perioperativen Myokardnekrose nach aortokoronaren Bypassoperationen" ✧ Schweizer Med Wochschr 49(Suppl):28 (1993) ✧ Hannes W, Zajonc H, Krause T, Gleichauf M, Keilich M, Schlosser V, Fasol R, Seitelberger R
23. "Einfluß von Diltiazem auf Ischaemie, Arrhythmien und postoperative Myokardfunktion nach aortokoronaren Bypassoperationen" ✧ Schweizer Med Wochschr 49(Suppl):15 (1993) ✧ Hannes W, Fasol R, Keilich M, Schlosser V, Seitelberger R
24. "Wertigkeit der Bestimmung postoperativer Enzymfreisetzungen nach aortokoronaren Bypassoperationen: Einfluß der Retransfusion von mediastinalem Drainageblut" ✧ Schweizer Med Wochschr 49(Suppl):15 (1993) ✧ Keilich M, Seitelberger R, Hannes W, Köster W, Zajonc H, Gleichauf M, Schlosser V, Fasol R
25. "Experimental growth of new coronary vascular structures in situ by the angiogenetic growth factor HBGF-I" ✧ J Mol Cell Cardiol 25(Suppl I):16 (1993) ✧ Fasol R, Schlaudraff K, Schumacher B, Seitelberger R, Schlosser V
26. "Diltiazem provides antiischemic and antiarrhythmic protection in patients undergoing coronary bypass grafting" ✧ J Mol Cell Cardiol 25(Suppl I):16 (1993) ✧ Hannes W, Zajonc H, Schlosser V, Fasol R, Seitelberger R
27. "Influence of angiotensin II on force of contraction and intracellular Ca2+ transients in human artrial myocardium” ✧ J Mol Cell Cardiol 25(Suppl I):16 (1993) ✧ Pieske B, Holubarsch Ch, Seitelberger R, Fasol R, Just H, Hasenfuss G
28. "Investigation of ATP as a sympathetic cotransmitter in human saphenous vein" ✧ Clin Pharmacol 7(7):379 (1993) ✧ Rump LC, Schaible U, Fasol R, Seitelberger R, von Kügelgen I
29. "Significance of troponin-t for the assessment of myocardial ischemia following coronary artery bypass surgery" ✧ Thorac Cardiovasc Surg 42(Suppl):1116-117 (1994) ✧ Keilich M, Fasol R, Hannes W, Köster W, Seitelberger R
30. "Coronary collateral growth induced by surgically implanted angiogenic growth factor in coronary artery patients: one-year follow-up" ✧ Thorac Cardiovasc Surg 44(Suppl):208 (1996) ✧ Fasol R, Fischlein T, Holubarsch Ch
31. "Transmyocardial channeling: a alternative to laser transmyocardial revascularization"✧ Thorac Cardiovasc Surg 44(Suppl):208 (1999) ✧ Slepian MJ, LePrince P, Toporoff B, Kern KB, Hilwig RW, Saadat V, Roeske WR, Fasol R, Copeland JG
32. "Rekonstruktion der Mitralklappe bei Prolaps-Syndrom (Barlow): eine Serie von 84 Patienten" ✧ Thorac Cardiovasc Surg 44(Suppl):208 (1999) ✧ Fasol R, Pfannmüller B, Zacher M, Stumpf J, Hacker R
33. "Plastik der Papillarmuskel zur Rekonstruktion ischämischer Mitralklappen-Insuffizienz" ✧ Thorac Cardiovasc Surg 44(Suppl):208 (1999) ✧ Fasol R, Pfannmüller B, Stumpf J, Hacker R
Patent
The US [PCT/US98/18652] & European [98944803.0-2305] Patent is directed to an artificial heart valve chordae, chordae sizing gauge and a method of using both to replace chordae for Mitral or Tricuspid valve repair. Chordae replacement is currently a routine technique for mitral repair operations.
